#$%^&*AU2016266059A120161222.pdf#####ABSTRACT This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.1/12 Figure 1: Overview of Botanical Drug Substance (BDS) preparation BRM Grow Cuttings taken from mother" plants After 11 weeks growing Harvest Plants time Good Agricultural Practice Dry and remove Controlled temperature stems and humidity 1 mm particle size Extraction Process Conversion of cannabinoid acid to neutral forms by Decaboxylate heating in nitrogen atmosphere Liquid C0 2 100 bar pressure E extraction 25C temperature Winterization Storage at -20-C in ethanol for defined time Good Manufacturing Practice Removal of precipitated Cold Filtration waxy material Recovery of BDS. Solvent Removal of Ethanol and Evaporation residual moisture BDSoato
