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ANALOGUES DE LA NIACINE SANS EFFETS DE BOUFFÉES CONGESTIVES ET PROCÉDÉS D'UTILISATION
专利权人:
TRUSTEES OF TUFTS COLLEGE
发明人:
申请号:
EP07799967.0
公开号:
EP2054386B1
申请日:
2007.08.01
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
One aspect of the present invention relates to substituted pyridines and pharmaceutically acceptable salts thereof that are active against a range of mammalian maladies. Another aspect of the invention relates to a pharmaceutical composition, comprising a compound of the present invention or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable excipient. The present invention also relates to methods of treating a range of mammalian maladies or conditions, including but not limited to hyperlipidemia, hypercholesterolemia, atherosclerosis, coronary artery disease, congestive heart failure, cardiovascular disease, hypertension, coronary heart disease, angina, pellagra, Hartnup's syndrome, carcinoid syndrome, arterial occlusive disease, obesity, hypothyroidism, vasoconstriction, osteoarthritis, rheumatoid arthritis, diabetes, Alzheimer's disease, lipodystrophy, or dyslipidemia, raising serum high-density lipoprotein (HDL) levels, and lowering serum low-density lipoprotein (LDL) levels.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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