Embodiments of the present invention relate to a MIMO detection method and apparatus for a transmit signal, including: removing one group of column vectors from an original channel matrix to generate a corresponding first channel matrix; multiplying a conjugate transpose matrix of a first matrix by the first channel matrix to obtain an equivalent channel matrix, and multiplying the conjugate transpose matrix of the first matrix by an original received signal vector to obtain an equivalent received signal vector; calculating a Euclidean distance between the equivalent received signal vector and a first vector to obtain a Euclidean distance set; obtaining a second transmit signal vector set by using the Euclidean distance set, and detecting a transmit signal vector according to the original received signal vector, the original channel matrix, the second transmit signal vector and the second transmit signal vector set. Therefore, a computation complexity is reduced.