Embodiments of the present disclosure comprise devices, systems and methods related to advanced wound therapy dressings. Specific embodiments are optimized for use with mobile continuous diffusion of oxygen therapy systems for the localized delivery of oxygen to damaged and healing tissues. Exemplary embodiments may utilize a conduit to deliver therapeutic fluids, including for example oxygen, whereby the conduit comprises a plurality of apertures or perforations. Exemplary embodiments may also comprise a spacer material with a plurality of distribution channels in fluid communication with the conduit.
