method of synthesis of the enzyme (7s) - 1 - (4 - dimethoxy bicyclo [4.2.0] octa - 1,3,5 - triene 7 - yl) methyl methanamine, and application to the synthesis of ivabradine and its salts
method of synthesis of the enzyme (7s) - 1 - (4 - dimethoxybicyclo [4.2.0] octa - 1,3,5 - triene 7 - yl) n - methyl methanamine, etapplication is the synthesis of the ivabradine and its selsproc u00c9d u00c9 enzyme synthesis of compound of formula (i), (7s) - 1 - (3.4 - dim u00c9thoxybicyclo (4.2).0] octa - 1,3,5 - tri u00c8ne 7 - yl) methyl m u00c9thanamine: application in the synthesis of ivabradine and its addition salts with a acidepharmaceutiquement acceptable.PROCEDE DE SYNTHESE ENZYMATIQUE DE LA (7S)-1-(3,4-DIMETHOXYBICYCLO[4.2.0]OCTA-1,3,5-TRIENE 7-YL) N-METHYL METHANAMINE, ETAPPLICATION A LA SYNTHESE DE L'IVABRADINE ET DE SES SELSPROCÉDÉ DE SYNTHÈSE ENZYMATIQUE DU COMPOSÉ DE FORMULE (I), LA (7S)-1-(3,4-DIMÉTHOXYBICYCLO[4.2.0] OCTA-1,3,5-TRIÈNE 7-YL) N-MÉTHYL MÉTHANAMINE :APPLICATION À LA SYNTHÈSE DE L'IVABRADINE ET DE SES SELS D'ADDITION À UN ACIDEPHARMACEUTIQUEMENT ACCEPTABLE.
