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PYRROLIDINONE ET PIPERIDINONE SPIRO A SUBSTITUTION DE TETRAHYDROPYRANNE, SA PREPARATION ET SON UTILISATION THERAPEUTIQUE
专利权人:
SANOFI
发明人:
GAO, ZHONGLI,HARTUNG, RYAN,STEFANY, DAVID
申请号:
CA2745715
公开号:
CA2745715C
申请日:
2009.12.04
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention discloses and claims a series of substituted N-phenyl-bipyrrolidine carboxamides of formula(I) Wherein R1, R2, m, n and p are as described herein. More specifically, thecompounds of this invention are modulators of H3receptors and are, therefore, useful as pharmaceutical agents, especially inthe treatment and/or prevention of a variety of diseasesmodulated by H3 receptors including diseases associated with the centralnervous system. Additionally, this invention alsodis-closes methods of preparation of substituted N-phenyl-bipyrrolidinecarboxamides and intermediates therefor.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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