An oncogcnc therapeutic drug which comprises a combination of a virus for an immunological treatment lo be administered for inducing a CTL reaction within the living bodywilh a carrier cell having been infected with an oncolytic virus before administration so as to treat a tumor cell with the vims within the living body. As the carrier cell, use can be made of, for example, an A549 cell. As the virus for an immunological treatment, use can be made of, for example, a non-proliferalivc adenovirus having been inactivated by UV irradiation. As the oncolytic virus, use can be made of, for example, a prolifcrativc adenovirus having a tumor-specific promoter.
