PROBLEM TO BE SOLVED: To provide a glaucoma model that can accurately reproduce the pathological condition of glaucoma.SOLUTION: An experimental apparatus (1) is provided that comprises: A) a pressurized container (2) B) a culture vessel (3) housing retinal tissue (5) and a culture solution (4) therein C) a gas blender (6) for blending two pressurized gases provided with an inert gas flow control valve (9) and an oxygen gas flow control valve (10) D) a gas injection pipe (12) E) a pressure control valve (14) F) a dissolved oxygen concentration sensor (16) G) a dissolved oxygen concentration input unit (18) which receives the measured value of the dissolved oxygen concentration sensor and which sets the dissolved oxygen concentration to any value. The experimental apparatus (1) further comprises a control device (11) controlling the inert gas flow control valve and/or the oxygen gas flow control valve such that the measured value of the dissolved oxygen concentration sensor matches the value set by the dissolved oxygen concentration input unit.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2018,JPO&INPIT【課題】本発明は、緑内障の病態を正確に再現できる緑内障モデルを提供することを目的とする。【解決手段】本発明は、 A)加圧容器(2)と、 B)網膜組織(5)と培養液(4)を内部に収容する培養容器(3)と、 C)不活性ガス流量制御弁(9)と、酸素ガス流量制御弁(10)を備え、二つの加圧ガスを混合するガス混合器(6)と、 D)ガス注入管(12)と、 E)圧力調節弁(14)と、 F)溶存酸素濃度センサ(16)と、 G)溶存酸素濃度センサの計測値を受信するとともに、溶存酸素濃度を任意の値に設定する溶存酸素濃度入力部(18)を備え、溶存酸素濃度センサの計測値が溶存酸素濃度入力部により設定された値と一致するように、不活性ガス流量制御弁及び/又は酸素ガス流量制御弁を制御する制御装置(11)とを有する実験装置(1)を提供する。【選択図】図1
