The present invention relates to a hemostatic composition, a hemostatic agent comprising the same, and a method for preparing same. The hemostatic composition comprises: a mussel adhesive protein as a first component and a bio-derived polymer other than the mussel adhesive protein as a second component. The present invention has excellent biocompatibility, biodegradability, hemostatic effects in underwater environments, and mechanical properties suitable for tissue environments.La présente invention concerne une composition hémostatique, un agent hémostatique comprenant celle-ci, et son procédé de préparation. La composition hémostatique comprend : une protéine adhésive de moule en tant que premier composant et un polymère dorigine biologique autre que la protéine adhésive de moule en tant que deuxième composant. La présente invention présente dexcellents biocompatibilité, biodégradabilité, effets hémostatiques dans des environnements sous-marins, et des propriétés mécaniques adaptées pour des environnements tissulaires.본 발명은 제1 성분으로서 홍합 접착 단백질 및 제2 성분으로서 홍합 접착 단백질 이외의 생체 유래 고분자를 포함하는 지혈용 조성물, 이를 포함하는 지혈제 및 그 제조 방법에 관한 것으로서, 우수한 생체적합성, 생분해성, 수중 환경에서의 지혈 효능 및 조직 환경에 적합한 기계적 물성을 가지는 것을 특징으로 한다.