PROBLEM TO BE SOLVED: To provide a kinesin inhibitor of motor protein which uses microtubules in a cell as a scaffold, and a composition useful in relaxation, prevention, and improvement of various pigmentation symptoms including stains and freckles.SOLUTION: There are provided a kinesin inhibitor having at least one or more types selected from iris florentina extract, rugosa rose extract, sandalwood extract, and great burnet extract as an active ingredient, and a pigmentation inhibitor based on kinesin inhibitory action. Furthermore, there is provided various types of composition (pharmaceutical composition, food and drink composition, cosmetic composition) containing the kinesin inhibitor.COPYRIGHT: (C)2015,JPO&INPIT【課題】細胞内の微小管を足場とするモーター蛋白質のキネシン(Kinesin)抑制剤、及びシミやソバカスを始めとする様々な色素沈着症状の緩和、予防・改善に有用な組成物の提供。【解決手段】シロバナイリス抽出物、ハマナス抽出物、ビャクダン抽出物、ワレモコウ抽出物から選ばれた少なくとも1種以上を有効成分とするキネシン抑制剤、及びキネシン抑制作用に基づく色素沈着抑制剤。更には、キネシン抑制剤を含有する各種組成物(医薬組成物、飲食品組成物、化粧料組成物)。【選択図】なし