BROECKX, RUDY LAURENT MARIA,FILLIERS, WALTER FERDINAND MARIA,NIESTE, PATRICK HUBERT J.,COPMANS, ALEX HERMAN,VANHOUTTE, FILIP MARCEL C.,LEYS, CARINA
申请号：
CA2864643
公开号：
CA2864643A1
申请日:
2013.03.13
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
There is provided inter alia a dry powder pharmaceutical formulation for inhalation comprising: (i) 6-(2-((4-amino-3-(3-hydroxyphenyl)-1 H-pyrazolo[3,4-d]pyrimidin-1-yl) methyl)-3- (2-chlorobenzyl)-4-oxo-3,4-dihydroquinazolin-5-yl)-N, N-bis(2-methoxyethyl)hex-5- ynamide or a pharmaceutically acceptable salt thereof, including all stereoisomers, tautomers and isotopic derivatives thereof and solvates thereof in particulate form as active ingredient； (ii) particulate lactose as carrier； and (iii) a particulate stabilizing agent selected from metal salts of stearic acid such as magnesium stearate and metal salts of stearyl fumarate.
