JENSEN ZOFFMANN, SANNAH,MATILE, HUGUES,ULLMER, CHRISTOPH
申请号：
CA2686238
公开号：
CA2686238C
申请日:
2008.05.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention provides an antibody directed to an epitope of a G -protein coupledreceptor, wherein the antibody binds to the extracellular N terminal region ofthe receptor andthe binding of the antibody to the G - protein coupled receptor inducesreceptor internalization incells, wherein the receptor is metabotropic glutamate receptor 7 (mGluR7) andwherein theantibody is produced by hybridoma cell line deposited with DSMZ as DSMACC2855.
