Noralvis Fleitas Salazar;Aniel Sanchez Puente;Vladimir A;Alejandro Miguel Martin Dunn;Monica Sarria Nunez;Osmany Guirola Cruz;Patricia Gabriela Toledo Mayora;Glay Chinea Santiago;Vivian Huerta Galindo
发明人:
Vivian Huerta Galindo,Glay Chinea Santiago,Noralvis Fleitas Salazar,Alejandro Miguel Martin Dunn,Monica Sarria Nunez,Osmany Guirola Cruz,Patricia Gabriela Toledo Mayora,Aniel Sanchez Puente,Vladimir A
申请号：
US12298808
公开号：
US08420311B2
申请日:
2007.04.26
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention is related to a method for blocking the infection of cells by dengue virus, based on interfering the direct interaction of the viral envelope protein with a cellular receptor or its indirect interaction with said cellular receptor through a carrier protein, as well as related uses； wherein said cellular receptor is the alpha-2 macroglobulin receptor, also known as the low density receptor-related protein or as CD91, and said carrier protein is human alpha-2 macroglobulin.
