Ieharu Hishinuma;Heather A. Davis;Fabian Gusovsky;André Lescarbeau;Yimin Jiang;Marc P;Kenzo Muramoto;Jane Daun;Bruce DeCosta;Kouichi Kikuchi;Seiichi Kobayashi;Toshihiko Kaneko;Norihito Ohi;Xiang-Yi Li
发明人:
Jane Daun,Heather A. Davis,Bruce DeCosta,Fabian Gusovsky,Ieharu Hishinuma,Yimin Jiang,Toshihiko Kaneko,Kouichi Kikuchi,Seiichi Kobayashi,André Lescarbeau,Xiang-Yi Li,Kenzo Muramoto,Norihito Ohi,Marc P
申请号:
US12917669
公开号:
US08691814B2
申请日:
2010.11.02
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides compounds having formula (I):wherein R1, R2, R3 and n are as described generally and in classes and subclasses herein,and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally.