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Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as RAF kinase inhibitors
专利权人:
Inc.;Millennium Pharmaceuticals
发明人:
Oslob, Johan D.,Zhu, Jiang,Barr, Kenneth,Crossrow, Jennifer,Raimundo, Brian,Tanaka, Hiroko
申请号:
AU2005316668
公开号:
AU2005316668B2
申请日:
2005.12.12
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention provides compounds having the formula: (I) wherein A-Btogether represents one of the following structures; (II), (III), (IV) and n,R, R, R, R, L, L,Y and Z are as defined in classes and subclasses herein, and pharmaceutical compositionsthereof, as described generally and in subclasses herein, which compounds areuseful as inhibitors of protein kinase (e.g., RAF), and thus are useful, for example,for the treatment of RAF mediated diseases.
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