Wu, Herren,Young, James F.,Watkins, Jeffry,Johnson, Leslie S.,Koenig, Scott,Huse, William
申请号：
AU2010202006
公开号：
AU2010202006B2
申请日:
2010.05.18
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2010202006B220120517.pdf#####Methods of Administering/Dosing Anti-RSV Antibodies for Prophylaxis and Treatment ABSTRACT 5 The present invention encompasses novel antibodies and fragments thereof which immunospecifically bind to one or more RSV antigens and compositions comprising said antibody fragments. The present invention encompasses methods preventing respiratory syncytial virus (RSV) infection in a human, comprising administering to said human a 10 prophylactically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention also encompasses methods for treating or ameliorating symptoms associated with a RSV infection in a human, comprising administering to said human a is therapeutically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention further encompasses compositions comprising antibodies or fragments thereof that immunospecifically bind to a SRV antigen, and methods using said compositions for 20 detection or diagnosis of a RSV infection.
