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Orodispersible tablet containing compacted sildenafil base
专利权人:
Max-Werner Scheiwe;Dieter Swatschek;Sven Winter
发明人:
Sven Winter,Max-Werner Scheiwe,Dieter Swatschek
申请号:
US13515515
公开号:
US08808739B2
申请日:
2010.12.22
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to a process for the preparation of a pharmaceutical intermediate, comprising the steps of (i) mixing (a-i) sildenafil base, (b-i) wicking agent, (c-i) disintegrant, (d-i) optionally glidant; (ii) compacting the mixture; and (iii) milling the compacted material; and to an intermediate obtainable by that process. In addition, the invention relates to a process for the preparation of an orally dispersible tablet (hereinafter also referred to as an “orodispersible tablet”) comprising the intermediate of the invention, and to orodispersible tablets obtainable by that process.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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