Disclosed herein is an isolated small RNA molecule. The small RNA molecule has an effect on inhibiting viral protein translation and growth of enterovirus. Therefore, also disclosed is use of the small RNA molecule for the preparation of a medicament for the treatment of an enterovirus infection.本發明揭示一種經分離的小RNA分子。該小RNA分子具有抑制腸病毒的病毒蛋白質轉譯以及生長之效用。因此,本發明亦揭示該小RNA分子供應用於製備一用來治療一腸病毒感染之醫藥品的用途。