The present invention provides a method for preparing and using equine influenza A virus isolated from a foal died of mortal pneumonia or genes or proteins thereof. The virus has specific substitution at 78th and 159th residues of HA. The present invention provides isolated nucleic acid molecules (polynucleotides) containing nucleic acid fragments corresponding to one or more viral proteins, a part of nucleic acid fragments of the viral proteins； and a complement of nucleic acid molecules. The present invention provides a vector, for example a plasmid encoding influenza virus proteins and(or) influenza vRNA (natural or recombinant vRNA).본 발명은 단리된 H3 말 인플루엔자 A 바이러스 및, 바이러스 및 유전자 또는 그들의 단백질의 제조 및 사용방법을 제공한다.
