A drug includes the relevant cranial vascular disease of Clinical Therapeutic Effects of Edaravone Brain circlulation insufficient (such as Ischemic Stroke), the structural formula (I) of pyrazolinone compounds comprising pharmaceutical effective amount: or its pharmaceutically acceptable salt or pseudopolymorphic forms, give control dosage, to make the plasma concentration of its original shape keep constant, therefore higher effect can be shown by this compound in predetermined period.
