Disclosed in the present invention is an eye drop for treating eye dryness. With a pH value of 5.0-7.0, the eye drop consists of the following components in percentage by weight: 0.05-0.1% of an active component 5-hydroxy-1-beta-D-furanose-1 H-imidazole-5-carboxamide, a proper amount of a pH value adjusting agent, 0.01-3% of an iso-osmotic agent, 0.003-0.5% of a bacteriostatic agent, 0.001-0.5% of a stabilizer, 0.01-0.5% of a tackifier, 2-5% of a solubilizer and the balance of water. The eye drop provided by the present invention can protect the epithelial barrier function of the corneas of a mouse with eye dryness and regain the number of goblet cells of the corneas, and can achieve relatively good anti-inflammatory and immune inhibition effects.
