КИССЕЛЬ Томас (DE),ПЕТЕРЗЕН Хольгер (CH),РЕНЕТТЕ Томас (DE),ЗАЙДЕЛЬ Нина (CH)
申请号：
RU2011128540/15
公开号：
RU2011128540A
申请日:
2009.12.14
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A pharmaceutical composition comprising nanoparticles comprising at least one pharmacologically active agent, at least one poly (ethylene carbonate) and optionally pharmaceutically acceptable excipients. The pharmaceutical composition according to claim 1 in the form of a suspension of nanoparticles. The pharmaceutical composition according to claim 1 or 2, which is a composition for parenteral administration. The pharmaceutical composition of claim 1, wherein the nanoparticles have a size of less than 1000 nm. The pharmaceutical composition of claim 4, wherein the nanoparticles have a size of less than 500 nm. The pharmaceutical composition of claim 1, wherein the molecular weight of the PEC polymer is less than 2000 kDa. The pharmaceutical composition of claim 6, wherein the molecular weight of the PEC polymer is less than 500 kDa. The pharmaceutical composition of claim 1, wherein the pharmacologically active agent is selected from the group consisting of chemical compounds, biologically active agents, nucleic acids, peptides and proteins. The pharmaceutical composition of claim 8, comprising a pharmacologically active agent, further selected from the group comprising a class of somatostatin analog inhibitors, bisphosphonates, lipid-modifying drugs and immunosuppressants. A suspension containing nanoparticles comprising at least one pharmacologically active agent and at least one poly (ethylene carbonate). 11. The suspension of claim 10, in which the poly (ethylene carbonate) has at least one of the following characteristics: (a) the content of ethylene carbonate is from 70 to 100 mol. %, (b) the intrinsic viscosity is from 0.4 to1. Фармацевтическая композиция, содержащая наночастицы, включающие по меньшей мере одно фармакологически активное средство, по меньшей мере один поли(этиленкарбонат) и необязательно фармацевтически приемлемые вспомогательные вещества.2. Фармацевтическая композиция по п.1 в виде суспензии наночастиц.3. Фармацевтическая композиция по п.
