The present invention provides a vascular intervention minimally invasive surgery teaching simulation device, which includes a virtual blood vessel module, a control module, and a sensing warning module. The virtual blood vessel module is designed to pass through a patient during catheter surgery. The blood vessel of is generated by 3D printing, the simulative blood vessel module has a first accommodating space and at least one sensing part formed in the first accommodating space, and the sensing part is provided with a second accommodating Space and a first connecting tube； the control module is connected to the immersive blood vessel module and controls the flow of liquid in the first tube； and the sensing and warning module includes a second connecting tube and a sensing and warning unit, One end of the second connecting pipe is connected to the first connecting pipe, and the other end is connected to the sensing and warning unit； wherein the sensing and warning unit generates a warning signal when the pressure of the second accommodating space changes.本發明提供一種血管介入微創手術教學模擬裝置其包含有一擬真血管模組、一控制模組及一感測警告模組，該擬真血管模組是依一病患進行導管手術時會經過的血管利用3D列印來產生之，該擬真血管模組具有一第一容置空間與至少一形成於該第一容置空間內的感測部，該感測部設有一第二容置空間及一第一連接管；該控制模組連接該擬真血管模組並控制液體在該第一管體內流動；以及該感測警告模組包含有一第二連接管及一感測警告單元，而該第二連接管一端連接該第一連接管，另端連接該感測警告單元；其中，該感測警告單元偵測該第二容置空間的壓力產生變化時會產生一警示訊號。
