The embodiments include preventing or reducing the progression of prostate cancer in mammals susceptible to developing prostate cancer, and reducing the incidence of clinically detected prostate cancer, using compositions containing compounds based on small neural thread peptides based on SEQ. ID. NO. 66 (IDQQVLSRIKLEIKRCL) and a pharmaceutically acceptable carrier. The embodiment includes, but is not limited to, administering the compounds intramuscularly, orally, intravenously, intraprostatically, intrathecally, intratumorally, intranasally, topically, transdermally, etc., either alone or conjugated to a carrier to a mammal in need thereof.
