Use of 3’-hydroxygenistein is disclosed. The 3’-hydroxygenistein has anti-allergy capability. Therefore the 3’-hydroxygenistein can be used to manufacture compositions for anti-allergy.本發明提供一種3’-羥基染料木黃酮之用途,所述3’-羥基染料木黃酮具有抑制過敏因子的功效。藉此,所述3’-羥基染料木黃酮可用於製備抑制過敏發生的組合物。