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DRUG FORMS FOR ORAL DELIVERY OF ADSORBENTS TO THE INTESTINE
专利权人:
ДА ВОЛТЕРРА (FR)
发明人:
ЛЕСКЮР Франсуа (FR),ДЕ ГАНЗБУРГ Жан (GB)
申请号:
RU2012140421/15
公开号:
RU2012140421A
申请日:
2011.02.23
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A composition comprising an adsorbent mixed with carrageenan, preferably in tablet form. The composition of claim 1, wherein the adsorbent is activated carbon. The composition according to claims 1 or 2, where carrageenan is kappa-carrageenan. 4. The composition according to claims 1 or 2, wherein the amount of carrageenan comprises between 5% and 25%, more preferably between 10% and 20% by weight of the composition. The composition of claim 3, wherein the amount of carrageenan comprises between 5% and 25%, more preferably between 10% and 20% by weight of the composition. A dosage form containing a core containing a composition according to any one of claims 1 to 4, and an outer coating layer formed around the core, so that the adsorbent is released from the form in the desired intestine. A mold according to claim 6, comprising a core containing a composition according to any one of claims 1 to 5, and an outer coating layer formed around the core, so that the adsorbent is released from the mold in the lower intestine. The form of claim 7, wherein the outer coating is a pH dependent enteric polymer. The form of claim 8, wherein the pH dependent enteric polymer is selected from the group consisting of cellulose trimellitate acetate (CAT), cellulose phthalate acetate (CAP), anionic copolymers based on methyl acrylate, methyl methacrylate and methacrylic acid, hydroxypropyl phthalate methyl cellulose ( , hydroxypropyl methylcellulose acetate succinate (HPMCAS), copolymers of methacrylic acid and ethyl acrylate, copolymer of methacrylic acid and ethyl acrylate, copolymers of methacrylic acid and methyl acrylate, (1: 1 ratio), methacrylic acid copolymers you and methyl acrylate, (1: 2 ratio), polyvinyl acetate phthalate (PVAP) and shellac resins. 10. The form of claims 8 or 9, where poly1. Композиция, содержащая адсорбент, смешанный с каррагенаном, предпочтительно в форме таблетки.2. Композиция по п.1, где адсорбент - это активированный уголь.3. Композиция по пп.1 или
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