An endoscopic biopsy instrument for obtaining a tissue sample from a body of a patient. The endoscopic biopsy instrument comprising a proximal portion (P) adapted to remain outside of the body of the patient in use and a distal portion (D) adapted to be inserted into the body of the patient in use. The endoscopic biopsy instrument further comprising a sleeve (9) and a motion transferring member (3). The distal end (3E) of the motion transferring member being adapted to be connected to a rotatable cutting tip (5) being extendable from a distal end of the sleeve and being configured to obtain a tissue sample from within the body of the patient using rotary motion. The endoscopic biopsy instrument further comprises a rotary motion element (1) for transferring rotary motion to the rotatable cutting tip a linear motion element (1) for extending and retracting the cutting tip from the distal portion of the sleeve and a lockable adjustment device (6 7 9A) for in situ adjusting and locking a maximum length that the rotatable cutting tip extends from the distal portion of the sleeve when being extended and retracted by the linear motion element.
