PURPOSE: A medicine box and a medicine management method are provided to manage medicine according to the state of medicine and to prevent a user from taking deteriorated medicine. CONSTITUTION: A medicine box comprises a storage unit(110) which stores medicine, an image acquisition unit(120) which takes a picture of objects, an input unit(160), and a controller(190). The controller obtains a first image which is the reference for determining the state of medicine and a second image of medicine, compares the first image with the second image, determines whether the medicine is deteriorated or not, and discharges, keeps, or discards the medicine in consideration of the determination result.본 발명은 약상자 및 약품관리방법에 관한 것이다. 보다 상세하게는, 본 발명은 변질된 약품을 폐기하는 약상자 및 변질된 약품을 폐기하는 약품관리방법에 관한 것이다.