您的位置: 首页 > 农业专利 > 详情页

VASCULARIZED TISSUE STRUCTURE WITH MICROFLUID PASSAGES AND PREPARATION METHOD THEREFOR
专利权人:
TSINGHUA UNIVERSITY
发明人:
WANG, Xiaohong,王小红,XU, Yufan,许雨帆
申请号:
CNCN2014/073954
公开号:
WO2015/106488A1
申请日:
2014.03.24
申请国别(地区):
WO
年份:
2015
代理人:
摘要:
The present invention relates to the technical field of tissue engineering and composite material forming. A vascularized tissue structure with microfluid passages and a preparation method therefor. The vascularized tissue structure comprises a tissue structure body, a branch vessel part, a capillary layer and a protective layer. By means of the present invention, composite forming of a dilute solution, cells and a hydrogel is realized. The tissue structure body is formed by spraying the hydrogel containing the cells, and the dilute solution containing or not containing the cells is distributed among grids of the hydrogel. Pores of branch vessels are reserved by the hydrogel containing the cells, the dilute solution containing or not containing the cells is distributed in the pores, and the wall of each branch vessel is a porous structure. The capillary layer is formed by coating or spraying a synthetic polymer dilute solution or the dilute solution containing the cells. The supporting part and the protective layer part are formed by stacking a synthetic or natural polymer solution. The formed structure is provided with vessel joints or a plurality of open-type passages at two ends thereof, and can be used for in-vivo transplantation or in-vitro culturing, so as to promote the development of vascularization.La présente invention concerne le domaine technique du génie tissulaire et de la formation de matériau composite. La présente invention concerne une structure de tissu vascularisé avec des passages microfluidiques et son procédé de préparation. La structure de tissu vascularisé comprend un corps de structure tissulaire, une partie de vaisseau ramifié, une couche capillaire et une couche protectrice. Au moyen de la présente invention, la formation dun composite à partir dune solution diluée, de cellules et dun hydrogel est réalisée. Le corps de structure tissulaire est formé par pulvérisation de lhydrogel contenant les cellules, et la solution diluée contenant ou
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充