Daniel Simon Peeper,Marjon Antoinetta Smit,Celia Jill Vogel
申请号:
US15023229
公开号:
US09629851B2
申请日:
2014.09.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The current disclosure relates to pharmaceutical combinations and compositions useful in the treatment of certain types of cancer. The disclosure also relates to method of treatment these certain types of cancer. In particular, the disclosure relates to the combined use of inhibitors of ROCK and proteins of the MAPK/ERK-pathway in the treatment of KRAS-, NRAS- or BRAF-mutated cancer, in particular in NRAS mutated melanoma.