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ENCAPSULATION OF PHARMACEUTICALS FOR TASTE MASKING IN CHEWABLE TABLETS
专利权人:
发明人:
David Platt
申请号:
US14775113
公开号:
US20160038410A1
申请日:
2014.03.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure relates to the use of polymers to coat bitter-tasting active pharmaceutical ingredients in a manner that masks the bitter taste of these compounds. Taste masked pharmaceutical formulations in which the particles of pharmaceutically active ingredients are coated with polymers or ion exchange resins are disclosed. The formulations provide taste masked pharmaceutical formulations in which the rapid disintegration of tablets is preserved. A method for preparing such coated particles in a fluidized bed coating process is disclosed. The polymer coating may include a combination of low molecular and high molecular weight water in-soluble polymers, plasticizer and fillers, which provides for a chewable dosage form having a pleasing taste thereby improving patient compliance.
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中国工程科技知识中心
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