This invention relates to a laminated tablet disintegrating in oral cavity comprising (1) a layer comprising an enteric fine particle containing proton pump inhibiting drug, and (2) a layer comprising acetylsalicylic acid, which is characterized in that the stability of the active ingredient (proton pump inhibiting drug, aspirin) of this tablet disintegrating in oral cavity is high, and the pharmacological effect of the active ingredient is stable and expressed rapidly after being applied.本發明係有關一種積層之口腔內崩解錠,係具有:(1)含有包含氫離子幫浦抑制劑之腸溶性細粒的層、以及(2)含有乙醯水楊酸的層。該口腔內崩解錠的特徵係活性成分(氫離子幫浦抑制劑、阿斯匹靈)之安定性高,且投予後活性成分之藥理效果會安定且迅速表現。
