THE UNITED STATES OF AMERICA; represented by the S
发明人:
申请号：
EP12738664.7
公开号：
EP2731626B1
申请日:
2012.06.27
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The present invention relates to compositions and method to kill cell. In particular embodiments, this method include contact have cell surface and therapeutically effective amount antibody-IR700 molecules, wherein the antibody specificity be bound to cell cortex protein, such as the tumour cell on tumour specific antigen surface. Unit is then illuminated, such as in 2 × 1 dosage of at least J of 660 to 740 wavelength. Also contact this cell with one or more therapeutic agents (such as drug), such as illumination unit after about 0 to 8 hour, to kill battery. Method of images cell killing real time monitoring is additionally provided, fluorescence lifetime imaging is utilized. Additionally providing a kind of includes wearable device clothes, jewelry, or covering It can be used for disclosed method to product with a NIR LED junctions conjunction.
