A kind of nasal cavity cleaning device, including drain part and gas-guide tube. Drain part includes reservoir, first jet lid and liquid sucking tube. First jet lid is the opening for being removably disposed what reservoir; Reservoir is connected with liquid sucking tube. Gas-guide tube has air inlet, port and leakage port. Air inlet and port are the both ends for setting what gas-guide tube respectively, and port is in a what reservoir and to install removably second nozzle lid; Leakage port is to open up between what air inlet and port, and be connected with air inlet and port, and one of reservoir slot bottom is set between what leakage port and port. This creation reaches the function of allowing user that can clean or replace nozzle by the design of removably nozzle cover, to reduce the waste of resource.一種鼻腔清潔裝置,包括導液件及導氣管。導液件包括有儲液槽、第一噴嘴蓋及汲液管。第一噴嘴蓋是可拆卸地設置於儲液槽之開口;儲液槽與汲液管相連通。導氣管具有進氣口、端口及洩氣口。進氣口與端口是分別設於導氣管之兩端,且端口是位於儲液槽內並裝設可拆卸地第二噴嘴蓋;洩氣口是開設於進氣口與端口之間,並與進氣口及端口相連通,且儲液槽之一槽底是設於洩氣口與端口之間。本創作藉由可拆卸地噴嘴蓋之設計,達到讓使用者可以清洗或更換噴嘴之功能,以減少資源的浪費。