Koc-Kan Ho;Irina Neagu;Andrew Laird Roughton;Ronald Palin;Michael Ohlmeyer;Steven G. Kultgen;Yajing Rong;Nasrin Ansari;Paul David Ratcliffe
发明人:
Andrew Laird Roughton,Koc-Kan Ho,Michael Ohlmeyer,Irina Neagu,Steven G. Kultgen,Nasrin Ansari,Yajing Rong,Paul David Ratcliffe,Ronald Palin
申请号:
US12671113
公开号:
US08211927B2
申请日:
2008.07.31
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to isoxazole-3-carboxamide derivative having the general Formula (I), or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of said isoxazole-3-carboxamide derivatives for the treatment of TRPV1 mediated disorders, such as acute and chronic pain disorders, acute and chronic neuropathic pain, acute and chronic inflammatory pain, respiratory diseases, and lower urinary tract disorders.