Steven G. Kultgen;Koc-Kan Ho;Ronald Palin;Andrew Laird Roughton;Paul David Ratcliffe
发明人:
Ronald Palin,Paul David Ratcliffe,Steven G. Kultgen,Koc-Kan Ho,Andrew Laird Roughton
申请号:
US13256553
公开号:
US20120071481A1
申请日:
2010.02.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to isoxazole-3-carboxamide derivative having the general Formula I or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of said isoxazole-3-carboxamide derivatives for the treatment of TRPV1 mediated disorders, such as acute and chronic pain disorders, acute and chronic neuropathic pain, acute and chronic inflammatory pain, respiratory diseases, and lower urinary tract disorders.