The device has a receiving element (21) for a lower part (2) of an active substance applicator (1) and comprising a circumferential pressure surface (22) and a receiving channel (23) for an applicator tube (7). The receiving element has a base element (24) and a cover element (25), where the channel is formed between the base and cover elements. The pressure surface extends over the base and cover elements such that a pressure surface section is formed on an upper side of the cover element for contacting a supporting surface section of the applicator. An independent claim is also included for a method for filling and closing an active substance applicator.
