compound for treating diseases or conditions by inhibiting the activity or expression of human gh, ghr, stat5, igf-1 and / or socs and proteins regulated by human gh, ghr, stat5, socs, igf-1 and insulin； compounds for treating diseases or conditions by inhibiting the activity or expression of human gh, ghr, stat5, socs, igf-1 and insulin and human gh, ghr, stat5, socs, igf-1 and insulin regulated proteins； method for treating diseases or conditions with changes in signaling genes related to human gh, ghr, stat5 and socs； and method for treating diseases or conditions caused by growth hormone a
MIN WEI,NOURI NEAMATI,PRIYA BALASUBRAMANIAN,VALTER D. LONGO
申请号：
BR112017017182
公开号：
BR112017017182A2
申请日:
2016.02.12
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
The present invention provides compounds and methods for treating diseases or conditions affected by the activity or expression of human gh, ghr, stat5, socs, igf-1, insulin related genes / proteins. Monoclonal antibodies are also provided for treating diseases or conditions related to growth hormone activity and growth hormone receptor activity.a presente invenção proporciona compostos e métodos para tratamento de doenças ou condições afetadas pela atividade ou expressão de genes/proteínas relacionados com gh, ghr, stat5, socs, igf-1, insulina humanos. são também proporcionados anticorpos monoclonais para tratamento de doenças ou condições relacionadas com a atividade de hormônios do crescimento e receptores de hormônios do crescimento.
