ALVEY, JOHN,GONZALEZ, JUAN M.,TAYLOR, BRADLEY J.,MORRIS, KRISTIN L.,ANTHONY, JOSHUA C.,TUCKER, HUGH N.,POELS, EDUARD K.
申请号:
CA2791177
公开号:
CA2791177C
申请日:
2011.02.24
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present disclosure provides formulations and methods for delivering water-soluble and lipid-soluble nutrients for preventing or correcting nutrient deficiencies to subjects requiring small-volume nutritional support, such as preterm infants. The formulations may comprise an emulsion of docosahexaenoic acid (DHA) stabilized by a protein emulsifier, such as alpha-lactalbumin, and may further comprise other valuable nutrients, such as arachidonic acid (ARA), arginine, glutamine, arginyl-glutamine dipeptide and/or alanyl-glutamine dipeptide. The formulation is useful, for example, for correcting nutritional deficiencies by increasing a subject's intake of nutrients such as omega-3 or omega-6 long-chain polyunsaturated acids, proteins, peptides, vitamins, minerals, other fatty acids, and/or essential amino acids. The nutritional formulation is suitable for enteral delivery and small-volume delivery via nasogastric tube, intragastric feeding, transpyloric administration and/or any other means of administration that result in the introduction of the nutritional formulation into the digestive tract of a subject.