ALVEY,JOHN,,MORRIS,KRISTIN L.,ANTHONY,JOSHUA C.,POELS,EDUARD K.,GONZALEZS, JUAN M.,TUCKER,HUGH N.,TAYLOR,BRADLEY J.
申请号：
MYPI 2012002803
公开号：
MY166570A
申请日:
2011.02.24
申请国别(地区):
MY
年份:
2018
代理人:
摘要：
THE PRESENT DISCLOSURE PROVIDES FORMULATIONS AND METHODS FOR DELIVERING WATER-SOLUBLE AND LIPID-SOLUBLE NUTRIENTS FOR PREVENTING OR CORRECTING NUTRIENT DEFICIENCIES TO SUBJECTS REQUIRING SMALL-VOLUME NUTRITIONAL SUPPORT, SUCH AS PRETERM INFANTS. THE FORMULATIONS MAY COMPRISE AN EMULSION OF DOCOSAHEXAENOIC ACID (DHA) STABILIZED BY A PROTEIN EMULSIFIER, SUCH AS ALPHA-LACTALBUMIN, AND MAY FURTHER COMPRISE OTHER VALUABLE NUTRIENTS, SUCH AS ARACHIDONIC ACID (ARA), ARGININE, GLUTAMINE, ARGINYL-GLUTAMINE DIPEPTIDE AND/OR ALANYL-GLUTAMINE DIPEPTIDE. THE FORMULATION IS USEFUL, FOR EXAMPLE, FOR CORRECTING NUTRITIONAL DEFICIENCIES BY INCREASING A SUBJECT’S INTAKE OF NUTRIENTS SUCH AS OMEGA-3 OR OMEGA-6 LONG-CHAIN POLYUNSATURATED ACIDS, PROTEINS, PEPTIDES, VITAMINS, MINERALS, OTHER FATTY ACIDS, AND/OR ESSENTIAL AMINO ACIDS. THE NUTRITIONAL FORMULATION IS SUITABLE FOR ENTERAL DELIVERY AND SMALL-VOLUME DELIVERY VIA NASOGASTRIC TUBE, INTRAGASTRIC FEEDING, TRANSPYLORIC ADMINISTRATION AND/OR ANY OTHER MEANS OF ADMINISTRATION THAT RESULT IN THE INTRODUCTION OF THE NUTRITIONAL FORMULATION INTO THE DIGESTIVE TRACT OF A SUBJECT. FIGURE 1
