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REGENERATED OXIDIZED CELULOSE BASED HEMOSTATIC MATERIALCONTAINING ANTIFIBROLYTIC AGENTS
专利权人:
Mevlut ERTAN
发明人:
Mevlut ERTAN
申请号:
US15568488
公开号:
US20180296723A1
申请日:
2015.04.21
申请国别(地区):
US
年份:
2018
代理人:
摘要:
In present invention oxidation method of viscon cellulose with NO2 obtained H3PO4/HNO3 is defined liquid and gas media. Regenerated oxidise cellulose (REOC in shorten term) contain in —COOH yields are standardised as 18.6-20.1 for textile, 19.8-21.5% for powder samples. Powder and textile (woven and fabric) products are impregnated 1.8-2.4% Ca+2 ion, 0-1.1% Na+1 ion, 0.8-1.5% tranexamic acid and 6-aminocaproic acid as antifibrinolytic. Obtained powder and gel products are impregnated Bi+3, Zn+2 and Ag+1 ions for antiseptic purposes. Only Bismuth of them is shown antibacterial effects. Also the aim of present invention is haemostat antimicrobial properties during impregnation of Rifampicin, Gatifloxacin, Doxycycline, Levofloxacin, Lincomycin, Clindamycin, Ciprofloxacin. Haemostatic properties are indicated for all products and antimicrobial properties are shown for some samples. Cytotoxicity, sensitivity and irritation properties are determined in compliance of Pharmacopeias.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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