RAITANO, ARTHUR B.,AFAR, DANIEL E. H.,JAKOBOVITS, AYA,FARIS, MARY,HUBERT, RENE S.,MITCHELL, STEVE C.,SAFFRAN, DOUGLAS C.
申请号:
CA2385032
公开号:
CA2385032C
申请日:
2000.10.05
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
A novel gene (designated PHOR-1) that is highly over-expressed in prostate andother cancers and its encoded proteinare described. PHOR-1 is a G protein-coupled receptor with homology toreceptors involved in olfaction. PHOR-1 in normal humantissues is restricted to prostate, and this gene is highly over-expressed inprostate cancer as well as in cancers of the kidney, uterus,cervix, stomach and rectum. Consequently, PHOR-1 provides a diagnostic and/ortherapeutic target for prostate cancer.