RAITANO, ARTHUR B.,AFAR, DANIEL E. H.,JAKOBOVITS, AYA,FARIS, MARY,HUBERT, RENE S.,MITCHELL, STEVE C.,SAFFRAN, DOUGLAS C.
申请号:
DK08165936
公开号:
DK2003202T3
申请日:
2000.10.05
申请国别(地区):
DK
年份:
2012
代理人:
摘要:
A novel gene (designated PHOR-1) that is highly over-expressed in prostate and other cancers and its encoded protein are described. PHOR-1 is a G protein-coupled receptor with homology to receptors involved in olfaction. PHOR-1 in normal human tissues is restricted to prostate, and this gene is highly over-expressed in prostate cancer as well as in cancers of the kidney, uterus, cervix, stomach and rectum. Consequently, PHOR-1 provides a diagnostic and/or therapeutic target for prostate cancer.