This invention regards the new resistance outflow characteristic formulation which includes with the hydrophilic colloid polymer of 2 kinds or more and the medicine active medicine of the effective quantity. This formulation has pH and resistance outflow characteristic consistency it makes with semi-solid viscosity method surrender value and simpler manufacturing and use of the medicine composition possible.< Selective figure >It is not本発明は、2種以上の親水コロイド重合体と有効量の医薬活性薬剤とを含む新規な耐流出性製剤に関する。本製剤は、半固体の粘度法降伏値と、医薬組成物のより簡単な調製と使用とを可能にするpH及び耐流出性粘稠度を有する。【選択図】なし