FROST, LISA, MARIE,COURTNEY, STEPHEN, MARTIN,BROOKFIELD, FREDERICK, ARTHUR,KALISH, VINCENT, J.
申请号:
EP09743703
公开号:
EP2278975A4
申请日:
2009.05.07
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention relates to nitroso derivatives including carboxylic acid and phosphoric acid esters of hydroxy nitroso compounds that donate nitroxyl (HNO) under physiological conditions. The compounds and compositions of the invention are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure, ischemia/reperfusion injury and cancer.