Stephen M. Courtney;Lisa M. Frost;Vincent J. Kalish;Frederick A. Brookfield
发明人:
Lisa M. Frost,Stephen M. Courtney,Frederick A. Brookfield,Vincent J. Kalish
申请号：
US12437512
公开号：
US08318705B2
申请日:
2009.05.07
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to nitroso derivatives including carboxylic acid and phosphoric acid esters of hydroxy nitroso compounds that donate nitroxyl (HNO) under physiological conditions. The compounds and compositions of the invention are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure, ischemia/reperfusion injury and cancer.
