Jie CHEN,Yan Chen,Ira B. Dicker,Richard A. Hartz,Nicholas A. Meanwell,Beata Nowicka-Sans,Alicia Regueiro-Ren,Sing-Yuen Sit,Ny Sin,Jacob Swidorski,Brian Lee Venables
申请号:
US16534208
公开号:
US20190359647A1
申请日:
2019.08.07
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula I:These compounds are useful for the treatment of HIV and AIDS.