A puncture injection instrument includes: a hollow needle body (10) having one or more projections (12) on a first surface of a substrate (11), each of the projections (12) being formed a through hole (13) penetrating from a distal end side of the projection (12) to a second surface of the substrate (11) opposite to the first surface; and an ultrasound probe (22). In the instrument, the ultrasound probe (22) is arranged outside a region in which the one or more projections (12) are formed.