David J. MISHELEVICH,Daniel Z. WETMORE,William J. TYLER,Tomo SATO
申请号：
US13734216
公开号：
US20140194726A1
申请日:
2013.01.04
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Disclosed are methods and systems for non-invasive neuromodulation using ultrasound for cognitive enhancement. Cognitive enhancement can be used for mitigation of abnormal conditions such as Alzheimer's Disease, Parkinson's Disease or stroke, or for enhancement in a normal individual. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training. Included is control of direction of the energy emission, intensity, frequency, pulse duration, pulse pattern, mechanical perturbation, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation.
