Peter Sean Cameron,Rachel E. Haurwitz,Andrew P. May,Christopher H. Nye,Megan van Overbeek
申请号：
US14836753
公开号：
US09970030B2
申请日:
2015.08.26
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Methods for use with Type II CRISPR-Cas9 systems for increasing Cas9-mediated genome engineering efficiency are disclosed. The methods can be used to decrease the number of off-target nucleic acid double-stranded breaks and/or to enhance homology-directed repair of a cleaved target nucleic acid.
